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Biochemistry news

Drug diversity in bacteria

Bacteria produce a cocktail of various bioactive natural products in order to survive in hostile environments with competing (micro)organisms. In the current issue of Nature Chemical Biology, researchers at Goethe University ...

date1 hour ago in Biochemistry
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The ABS of molecular engines

Peroxisomes are cell organelles that carry out a number of functions, including the degradation of cytotoxins. For this purpose, they require enzymes that have to be transported into peroxisomes via complicated machinery. ...

dateMar 08, 2019 in Biochemistry
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Seawater bacteria provides leads to fight melanoma

Malignant melanoma can be a particularly dangerous form of cancer, and more therapeutic options are needed. Now, researchers report in ACS Medicinal Chemistry Letters that a bacteria from seawater has inspired promising leads ...

dateMar 06, 2019 in Biochemistry
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Structural insights into tiny bacterial harpoons

New research sheds light onto how different bacterial species can build complex nano-harpoons with different protein building blocks. Bacteria use these harpoons called Type VI secretion systems to inject toxins into nearby ...

New antibiotic named after Leiden

Increasing resistance and a lack of new antibiotics are a serious problem for public health. Against this background, Gilles van Wezel of the Institute of Biology Leiden is looking for new medicines. Together with former ...

Thermodynamic properties of hevein

Hevein is a small protein (4.7 kDa) consisting of forty-three amino acid residues. It is the main component of the bottom fraction of rubber tree (Hevea brasiliensis) latex that has a pronounced antimicrobial activity, thus ...

Structure of fat-processing enzyme determined

After decades of work with no success, researchers have determined the high-resolution, three-dimensional structure for lipoprotein lipase, the enzyme that processes fats, or triglycerides, in the bloodstream and releases ...

How a certain bacterium communicates and makes us sick

Researchers at Binghamton University, State University of New York have uncovered the unique way in which a type of Gram-negative bacterium delivers the toxins that make us sick. Understanding this mechanism may help design ...

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